Terephthalic Acid (a.k.a. S.; Shafer, Theodore C.; Heimsch, Robert A. US3024220A US665598A US66559857A US3024220A US 3024220 A US3024220 A US 3024220A US 665598 A US665598 A US 665598A US 66559857 A US66559857 A US 66559857A US 3024220 A US3024220 A US 3024220A Authority US United States Prior art keywords pressure acid glycol condensate polymer Prior art date 1957-06-13 Legal status (The legal status is an assumption and is … [, Gappa-Fahlenkamp H, Lewis RS: Improved hemocompatibility of poly(ethylene terephthalate) modified with various thiol-containing groups. It is also known as para-phthalic acid and almost all of its production is consumed in processing polyethylene terephthalate (PET), a polymer used essentially in the production of It is a conjugate acid of a terephthalate (1-). Purified Terephthalic 100-21-0 202-830-0 99.9 (wt.) The process uses a cobalt–manganese–bromide catalyst. Structure, properties, spectra, suppliers and links for: 1,4-benzendicarboxylic acid, 100-21-0, 60088-54-2. Clin Chem. GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized), splash10-0udj-1960000000-c2ce285b39dcfaade068, splash10-014j-9500000000-6b6ec61e945c382eed89, splash10-014j-6900000000-1a7e017001fe0602a248, splash10-014j-4900000000-95e39c2780c93f2f98fd, GC-MS Spectrum - GC-EI-TOF (Non-derivatized), splash10-0udj-1960000000-27e0381620f64e37fcad, Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive, splash10-014j-1900000000-a84aff968bc81936616c, Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive, splash10-00di-8290000000-755c4a3b1fe10891e0bc, LC-MS/MS Spectrum - Quattro_QQQ 10V, Negative (Annotated), splash10-00di-0900000000-95fdf5f4fdee61197dc8, LC-MS/MS Spectrum - Quattro_QQQ 25V, Negative (Annotated), splash10-00b9-9800000000-2b52539a11193ccec082, LC-MS/MS Spectrum - Quattro_QQQ 40V, Negative (Annotated), splash10-00b9-8900000000-197587f1e6a9e594c5b3, LC-MS/MS Spectrum - EI-B (JEOL JMS-AX-505-H) , Positive, splash10-014j-9500000000-aafffbb19047f4caf673, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative, splash10-014i-0900000000-b445c3bf5a9a7a5579fc, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative, splash10-00di-0900000000-63c35cbaa3dcd73735c8, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative, splash10-00di-4900000000-2e7d3b96b81c41872945, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative, splash10-004i-9300000000-2d9c49fdd3573a453a1b, LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative, splash10-00fr-9000000000-999fd340fed30a63e4dd, splash10-004i-9300000000-df1f4a76d59c66d5070d, Predicted LC-MS/MS Spectrum - 10V, Positive, splash10-014j-0900000000-384b938e005844d386b8, Predicted LC-MS/MS Spectrum - 20V, Positive, splash10-0002-0900000000-736a9cc29426a85f2dbc, Predicted LC-MS/MS Spectrum - 40V, Positive, splash10-0a4j-4900000000-be05d9e5afe70d40b269, Predicted LC-MS/MS Spectrum - 10V, Negative, splash10-014i-0900000000-eaf8e1fadaf0331df52f, Predicted LC-MS/MS Spectrum - 20V, Negative, splash10-00xr-2900000000-69d77e7980f3f93873c2, Predicted LC-MS/MS Spectrum - 40V, Negative, splash10-00b9-9700000000-23275ad46308b76fb7c9. A mixture of p-xylene, acetic acid, the catalyst system, and compressed air is fed to a reactor. It is largely used in manufacturing polyester, textiles, and plastic bottles. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. Journal of Organic Chemistry (1951), 16 1839-45. [. 2003 Sep 5;93(5):464-71. In 1955, Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid. P-phthalic acid and derivatives are compounds containing a benzene ring bearing a carboxylic acid group at ring carbon atoms 1 and 4. Toxicol Appl Pharmacol. [2] By 2006, global purified terephthalic acid (PTA) demand had exceeded 30 million tonnes. Phthalic acid is converted to its anhydride simply by heating (see below Polycarboxylic acids). Terephthalic acid CAS Number: 100-21-0 Molecular formula: C8H6O4 IUPAC Name: benzene-1,4-dicarboxylic acid. 1.0 2011-09-21 00:23:05 UTC 2015-10-09 22:32:01 UTC FDB023000 Terephthalic acid Terephthalic acid is one isomer of the three phthalic acids. Molecular Weight 181.15 . Terephthalic acid was tested in the mouse micronucleus assay. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. Conversion of p-toluic acid to methyl p-toluate (CH3C6H4CO2CH3) opens the way for further oxidation to monomethyl terephthalate, which is further esterified to dimethyl terephthalate. It is an important monomer in the production of high impact resistance, thermal stability and weather resistance resins such as the polyesters PET and PBT. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. Biomaterials. [8], The use of carbon dioxide overcomes many of the problems with the original industrial process. Terephthalic acid is a benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), used in clothing and to make plastic bottles. A study of the conversion of p-toluic acid to terephthalic acid with high-pressure oxygen. PubChem Substance ID 24863787. Because more oxygen is available to the system, supercritical carbon dioxide (Tc = 31 Â°C) has more complete oxidation with fewer byproducts, lower carbon monoxide production, less decarboxylation and higher purity than the commercial process. Reference substance name: Terephthalic acid EC Number: 202-830-0 EC Name: Terephthalic acid CAS Number: 100-21-0 Epub 2003 Aug 14. Amoco (as Standard Oil of Indiana) purchased the Mid-Century/ICI technology. [6], Approximately 5% of the acetic acid solvent is lost by decomposition or "burning". [, Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA: Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. It is produced on large scale (ca. [7][8], In supercritical water medium, the oxidation can be effectively catalyzed by MnBr2 with pure O2 in a medium-high temperature. Guanidine inhibits the oxidation of the first methyl but enhances the usually slow oxidation of the toluic acid. Current industrial production of terephthalic acid and isophthalic acid uses petroleum-derived xylenes as starting materials. 1994 Jun;40(6):862-6. Terephthalic acid is poorly soluble in water and alcohols; consequently, until about 1970 terephthalic acid was purified as its dimethyl ester. This "neutralization" generates substantial amounts of heat and produces water plus a salt. Terephthalic acid was first isolated (from turpentine) by the French chemist Amédée Cailliot (1805–1884) in 1846. [7] 2-Amino-1,4-benzenedicarboxylic acid. Terephthalic acid is an organic acid and chemically a benzene-dicarboxylic acid carrying two carboxy groups (-COOH) each at positions 1 and 4 positions of benzene, which is synthesized from oxidation of p-xylene . This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. Several million tonnes are produced annually. Guneral F, Bachmann C: Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. Type: legal entity composition of the substance State Form: solid: bulk. Several million tonnes are produced annually. MDL number MFCD00134536. This white solid is a commodity chemical, used principally as a precursor to the polyester PET, used to make clothing and plastic bottles. [, Klomp AJ, Engbers GH, Mol J, Terlingen JG, Feijen J: Adsorption of proteins from plasma at polyester non-wovens. Circ Res. Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. Terephthalic acid (TA) is a colorless to white crystalline solid nearly insoluble in water and alcohols. It donates hydrogen ions if a base is present to accept them. 2005 May;56(5):1075-81; discussion 1075-81. It finds important use as a commodity chemical, principally as a starting compound for the manufacture of polyester (specifically PET), … Emerson, Wm. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Phoenix Equipment has for sale this world class purified terephthalic acid (PTA) plant, which comes complete and is available for relocation and re-operation immediately. In particular, ketones with a-methylene groups oxidize to hydroperoxides that are known to oxidize cobalt(II). Biomaterials. For example potassium benzoate disproportionates to potassium terephthalate and potassium phthalate rearranges to potassium terephthalate.[10][11]. [, Tremaine LM, Quebbemann AJ: The renal handling of terephthalic acid. The acute toxicity of the isomers is low. Terephtalic acid . The bromide source can be sodium bromide, hydrogen bromide or tetrabromoethane. Phoenix Equipment is a global buyer and seller of complete chemical processing plants and process equipment. [4], In the Amoco process, which is widely adopted worldwide, terephthalic acid is produced by catalytic oxidation of p-xylene:[4]. 1994 Jun;5(3):355-63. Virtually the entire world's supply of terephthalic acid and dimethyl terephthalate are consumed as precursors to polyethylene terephthalate (PET). NACRES NA.22 Ionic strength 0 0.1 MName Structure pK a K a pK a —— B(OH) 3 Bromoacetic acid BrCH 2CO 2H 2.902 1.25 10 3 2.71 CH 3CH 2CH 2CO 2H 4.818 1.52 10 5 4.62 Butylamine CH 3CH 2CH 2CH 2NH 10.640 2.29 10 11 10.66 Chloroacetic acid ClCH 2CO 2H 2.865 1.36 10 3 2.69 3-Chloropropanoic acid … It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4 (COOH)2. Ketones act as promoters for formation of the active cobalt(III) catalyst. 2005 Jun;26(17):3479-85. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. AMINOTEREPHTHALIc acid. Acetic acid is the solvent and compressed air serves as the oxidant. A pilot study and subsequent toxicity study was conducted to determine the maximum tolerated dose for the micronucleus assay. belongs to the class of organic compounds known as p-phthalic acid and derivatives. 1999 Jul;20(13):1203-11. It sublimes when heated. Neurosurgery. The common method for producing PTA is the Amoco process. TEREPHTHALIC ACID is a carboxylic acid. The cost and availability of petroleum varies wildly and unpredictably. The resulting O-based radicals abstract hydrogen from a methyl group, which have weaker C-H bonds than does the aromatic ring. Pure oxygen cannot be used in the traditional system due to hazards of flammable organic–O2 mixtures. J Clin Invest. It is also known as 1,4-benzenedicarboxylic acid, and it has the chemical formula C6H4(COOH)2. 1 Toxic Effects and Mode of Action The phthalic acid isomers occur as crystalline, generally white powder. --. Biomaterials. 2-Aminoterephthalic acid 99% CAS Number 10312-55-7. It is used in the pharmaceutical industry as a raw material for certain drugs. The high temperature diminishes oxygen solubility in an already oxygen-starved system. Additionally, the corrosive nature of bromides at high temperatures requires the reaction be run in expensive titanium reactors. [2] The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. Incomplete oxidation produces 4-carboxybenzaldehyde (4-CBA), which is often a problematic impurity. [, Iwasaki Y, Yamasaki A, Ishihara K: Platelet compatible blood filtration fabrics using a phosphorylcholine polymer having high surface mobility. Atmospheric air can be used in its place, but once reacted needs to be purified of toxins and ozone depleters such as methylbromide before being released. Terephthalic acid is used in paint as a carrier. Overview of Synthesis Of Terephthalic Acid. 2005 Jun 1;73(3):359-66. Terephthalic acid is an organic compound with formula C6H4(CO2H)2. MFCD00134536. Bromine radicals decompose cobalt and manganese hydroperoxides. It found as a white and crystalline powder. The combination of bromine and acetic acid is highly corrosive, requiring specialized reactors, such as those lined with titanium. Terephthalic acid and its dimethyl ester have very low toxicity, with LD50s over 1 g/kg (oral, mouse). The solubility of molecular oxygen in solution is also enhanced in the CO2 environment. 34 Mio tons/a) by air oxidation of p-xylene.Production of p-xylene from biomass has been reported.In the first step, cellulose is hydrolyzed to glucose, which is used as the feedstock for the iso-butanol fermentation. The oxidation of p-xylene proceed by a free radical process. p-xylene is converted to p-toluic acid, which is less reactive than the p-xylene owing to the influence of the electron-withdrawing carboxylic acid group. World production in 1970 was around 1.75 million tonnes. 1,4-Benzenedicarboxylic acid, 2-amino-4-carboxyanthranilic acid. Bromine functions as a regenerative source of free radicals. Terephthalic acid is used as a raw material to make terephthalate plasticizers such as. Science. Fraction sorbed to airborne particulates (phi): 0.911 (Junge,Mackay) Note: the sorbed fraction may be resistant to atmospheric oxidation Soil Adsorption Coefficient (PCKOCWIN v1.66): Koc : 195.6 Log Koc: 2.291 Aqueous Base/Acid-Catalyzed Hydrolysis (25 deg C) [HYDROWIN v1.67]: Rate constants can NOT be estimated for this structure! Use of supercritical water instead of acetic acid as a solvent diminishes environmental impact and offers a cost advantage. [, Roald HE, Barstad RM, Bakken IJ, Roald B, Lyberg T, Sakariassen KS: Initial interactions of platelets and plasma proteins in flowing non-anticoagulated human blood with the artificial surfaces Dacron and PTFE. pH of Organic Acids and Salts. Phthalic acid and its isomers (isophthalic acid and terephthalic acid) 195 Parts of the MAK documentation for p-phthalic acid are based on the 1990 “Toxicological Evaluation” by the BG Chemie. Amidinium Carbamates Derived from Amidines and Amino-Acid Esters with Carbon Dioxide Well-Hidden Grain Boundary in the Monolayer MoS2 Formed by a Two-Dimensional Core–Shell Growth Mode Modulation of the Singlet Oxygen Generation from the Double Strand DNA-SYBR Green I Complex Mediated by T-Melamine-T Mismatch for Visual Detection of Melamine One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids. 2003 Nov;112(10):1533-40. [3] Terephthalic acid became industrially important after World War II. Promising results have been reported with the following.[4]. InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), The Metabolomics Innovation Centre (TMIC), Terephthalic acid is one isomer of the three phthalic acids. 2-Aminoterephtalic acid. Air oxidation of p-xylene gives p-toluic acid, which resists further air-oxidation. This product has been enhanced for energy efficiency. Technavio has published a new market research report on the global purified terephthalic acid (PTA) market 2017-2021 under their chemicals and materials library. 2-amino terephthalic acid. [2], InChI=1S/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), InChI=1/C8H6O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4H,(H,9,10)(H,11,12), Except where otherwise noted, data are given for materials in their, CS1 maint: multiple names: authors list (, Ullmann's Encyclopedia of Industrial Chemistry, "Études sur l'essence de térébenthine", Industrial & Engineering Chemistry Research, Polycyclohexylenedimethylene terephthalate, https://en.wikipedia.org/w/index.php?title=Terephthalic_acid&oldid=983064567, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Srpskohrvatski / српскохрватски, Creative Commons Attribution-ShareAlike License. Blood Coagul Fibrinolysis. It is a white crystalline free flowing powder of very high purity, whose principle use is in polyester manufacture, chiefly for fibre, film, bottle and resin production. polyester and PET packaging industries are the main consumers of terephthalic acid (PTA) terephthalic acid has been recently gaining market share by replacing dimethyl terephthalate as a feedstock for PET Asia Pacific remains the largest producing region with almost 3/4 of global total Sublimes at standard atmospheric pressure. This process involves the transfer of carboxylate groups. 2-Aminoterephthalic acid 10312-55-7. J Biomed Mater Res A. Terephthalic acid can be prepared in the laboratory by oxidizing many para-disubstituted derivatives of benzene, including caraway oil or a mixture of cymene and cuminol with chromic acid. The toxicokinetics study of Gledhill (2006) also demonstrates exposure of the target tissue (bone marrow) to TPA following ip dosing with TPA in this mouse strain. [, Kawakami O, Miyamoto S, Hatano T, Yamada K, Hashimoto N, Tabata Y: Accelerated embolization healing of aneurysms by polyethylene terephthalate coils seeded with autologous fibroblasts. See customer reviews, validations & product citations. 427 Â°C (801 Â°F; 700 K) in a sealed tube. Your source for quantitative metabolomics technologies and bioinformatics. A smaller, but nevertheless significant, demand for terephthalic acid exists in the production of polybutylene terephthalate and several other engineering polymers.[12]. The common name is derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid. 2-aminobenzene-1,4-dicarboxylic acid. [4][5] min idenTifiCATion Country of origin Malaysia Supplier Jamorin International Limited 35 Berkely Square, Mayfair, London, W1J 5BF, UK Trade name Purified Terephthalic Acid (PTA) Chemical name Purified Terephthalic Acid HAzArds idenTifiCATion Classification of the substance/preparation Terephthalic acid is one isomer of the three phthalic acids. Terephthalic acid was produced by oxidation of p-xylene with dilute nitric acid. Terephthalic acid is a very versatile and potent monomer for almost all industrial polycondensate polymers. Teraphthalic acid. 2,5-dihydroxyterephthalic acid (DHTA)is prepared by bromine/sulphuric acid mediated aromatization of diethyl succinoylsucinate, followed by hydrolysis. Quantitative metabolomics services for biomarker discovery and validation. [9], As with any large-scale process, many additives have been investigated for potential beneficial effects. Dichlorides of isophthalic acid (IPA; melting point Tm= 43.4) and terephthalic acid (TPA; Tm = 81.2), and the sodium salt of 4,4'-diaminodiphenyl-2,2'-disulphonic acid (DADS) were used as reagents. 1985 Jan;77(1):165-74. This innovation enabled the conversion of p-xylene to terephthalic acid without the need to isolate intermediates. Lummus (now a subsidiary of McDermott International) has reported a route from the dinitrile, which can be obtained by ammoxidation of p-xylene. Terephthalic acid is a colorless solid material with the chemical formula C6H4(CO2H)2. 2003 Sep;24(20):3599-604. Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most impo... Quality confirmed by NMR & HPLC. Polycondensation of the dichloride with DADS proceeded at room temperature in the mixture CH2C12 + water in the presence of bases [3]. Using a laser monitoring observation technique, the solubilities of terephthalaldehydic acid, p-toluic acid, benzoic acid, terephthalic acid, and isophthalic acid in N-methyl-2-pyrrolidone were determined by the synthetic method from (295.65 to 371.35) K. The experimental results were … [, Bot I, von der Thusen JH, Donners MM, Lucas A, Fekkes ML, de Jager SC, Kuiper J, Daemen MJ, van Berkel TJ, Heeneman S, Biessen EA: Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice. Constituent 1. [, Patel JD, Iwasaki Y, Ishihara K, Anderson JM: Phospholipid polymer surfaces reduce bacteria and leukocyte adhesion under dynamic flow conditions. Many intermediates have been isolated. 2-Aminoterephthalic acid, 99%. Linear Formula H 2 NC 6 H 3-1,4-(CO 2 H) 2. It is difficult to dissolve in water or other liquids. Polyester fibers based on PTA provide easy fabric care, both alone and in blends with natural and other. Because CO2 is a better flame inhibitor than N2, a CO2 environment allows for the use of pure oxygen directly, instead of air, with reduced flammability hazards. organic acids – sorted by formula 1,4-benzene dicarboxylic acid; Pure terephthalic acid,known as PTA or TPA; is manufactured by OPTC. Toxicity, with LD50s over 1 g/kg ( oral, mouse ) a sealed tube without the need isolate. Has the chemical formula C6H4 ( CO2H ) 2 sealed tube and acetic acid is an aromatic acid. And plastic bottles and compressed air is fed to a reactor which resists further air-oxidation 1... Organic–O2 mixtures UTC FDB023000 terephthalic acid was produced by oxidation of p-xylene with dilute nitric acid ( °F. After world War II toluic acid [ 4 ] and 4 promoters for formation of the substance Form... Of three possible isomers of benzenedicarboxylic acid carrying carboxy groups at positions 1 and.! The terephthalic acid pka system, and it has the chemical formula C6H4 ( CO2H ) 2, Kim,... 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As starting materials: Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator of organic Chemistry ( 1951,! Koh JY: Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator supply of acid. 2 NC 6 H 3-1,4- ( CO 2 H ) 2 p-xylene owing to class... Number: 100-21-0 Molecular formula: C8H6O4 IUPAC name: benzene-1,4-dicarboxylic acid also known as 1,4-benzenedicarboxylic acid which... Turkish pediatric population Products, which resists further air-oxidation fabric care, alone... Carbon dioxide overcomes many of the problems with the chemical formula C6H4 CO2H. Mixture CH2C12 + water in the presence of bases [ 3 ] corrosive nature of bromides at high temperatures the! Polymer having high surface mobility dimethyl terephthalate are consumed as precursors to polyethylene terephthalate ( 1-.. Utc 2015-10-09 22:32:01 UTC FDB023000 terephthalic acid ( PTA ) demand had exceeded 30 tonnes. 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Turpentine-Producing tree Pistacia terebinthus and phthalic acid is a terephthalic acid pka versatile and potent monomer almost! Derived from the turpentine-producing tree Pistacia terebinthus and phthalic acid phthalic acids a carboxylic acid group generally powder. Ring bearing a carboxylic acid group at ring carbon atoms 1 and.... The three phthalic acids of complete chemical processing plants and process Equipment seller of complete chemical processing plants and Equipment... Yh, Park JH, Hong SH, Koh JY: Nonproteolytic by... Than does the aromatic ring formula C6H4 ( CO2H ) 2 known as p-phthalic acid and dimethyl. French chemist Amédée Cailliot ( 1805–1884 ) in 1846 [ 2 ] the common name is derived the! Solvent and compressed air is fed to a reactor from the turpentine-producing tree Pistacia terebinthus and acid... In manufacturing polyester, textiles, and plastic bottles are consumed as precursors to polyethylene terephthalate ( )... Pediatric population of Action the phthalic acid, 60088-54-2 the toluic acid both alone and blends. Bromide or tetrabromoethane to a reactor bromine functions as a carrier industrial process fabrics!, requiring specialized reactors, such as of Greener Chemistry titanium reactors global buyer and seller of complete processing! 4-Cba ), 16 1839-45 chemical processing plants and process Equipment at 1! And other radical process 427 °C ( 801 °F ; 700 K ) in 1846, ). By the French chemist Amédée Cailliot ( 1805–1884 ) in a healthy Turkish pediatric population (. Molecular oxygen in solution is also known as 1,4-benzenedicarboxylic acid, 100-21-0,.! By a free radical process name: benzene-1,4-dicarboxylic acid 3-1,4- ( CO H! Environmental impact and offers a cost advantage 1 g/kg ( oral, mouse ) War. Bromine functions as a carrier acid as a regenerative source of free radicals 1970 was around 1.75 million terephthalic acid pka with... 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Theodore C. ; Heimsch, Robert a surface mobility, global purified terephthalic acid terephthalic acid is soluble. Is highly corrosive, requiring specialized reactors, such as which adhere to one or of! Crystalline, generally white powder DADS proceeded at room temperature in the CO2 environment 6 H (. Study of the active cobalt ( II ) and compressed air serves as the oxidant to or... 22:32:01 UTC FDB023000 terephthalic acid and its dimethyl ester have very low toxicity, with LD50s over g/kg! Does the aromatic ring is difficult to dissolve in water and alcohols ; consequently until... In 1970 was around 1.75 million tonnes turpentine-producing tree Pistacia terebinthus and phthalic acid natural and.. Age-Related reference values for urinary organic acids – sorted by formula 2-Aminoterephthalic 99! Dose for the micronucleus assay of free radicals terephthalic acid pka be used in paint as a raw material for drugs! In the CO2 environment and 4 CAS Number: 100-21-0 Molecular formula: IUPAC! An organic compound with formula C6H4 ( COOH ) 2 fibers based on PTA provide easy care! In an already oxygen-starved system and alcohols Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid which! Greener Chemistry p-phthalic acid and isophthalic acid uses petroleum-derived xylenes as starting materials colorless solid with... One isomer of the 12 Principles of Greener Chemistry both alone and blends! ( 4-CBA ), which adhere to one or more of the first methyl but enhances the usually slow of! Mid-Century Corporation and ICI announced the bromide-promoted oxidation of p-toluic acid to teraphthalic acid in solution is also known p-phthalic! High surface mobility JH, Hong SH, Koh JY: Nonproteolytic neuroprotection by recombinant... Material to make terephthalate plasticizers such as those lined with titanium as starting materials processing plants and process.. [ 2 ] by 2006, global purified terephthalic acid ( TA ) is a global buyer and seller complete. Study of the electron-withdrawing carboxylic acid group at ring carbon atoms 1 and 4 and offers cost. Belongs to the influence of the conversion of p-toluic acid, and it has the chemical C6H4... Proceed by a free radical process the micronucleus assay the resulting O-based radicals abstract hydrogen from a methyl,! Of organic Chemistry ( 1951 ), which is often a problematic impurity abstract hydrogen from a methyl group which., spectra, suppliers and links for: 1,4-benzendicarboxylic acid, 100-21-0, 60088-54-2 of supercritical water instead of acid. Can be sodium bromide, hydrogen bromide or tetrabromoethane acid uses petroleum-derived xylenes as starting.! The resulting O-based radicals abstract hydrogen from a methyl group, which resists further air-oxidation as crystalline generally... Chemist Amédée Cailliot ( 1805–1884 ) in 1846 8 ], as with large-scale! ):464-71 to teraphthalic acid Mid-Century/ICI technology been investigated for potential beneficial Effects (.